Signaling pathways in rheumatoid arthritis: implications for targeted therapy.

ABSTRACT: Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease progression leads to joint deformity and associated loss of function, which significantly impacts the quality of life for sufferers and adds to losses in the labor force. In the past few decades, RA has attracted increased attention from researchers, the abnormal signaling pathways in RA are a very important research field in the diagnosis and treatment of RA, which provides important evidence for understanding this complex disease and developing novel RA-linked intervention targets. The current review intends to provide a comprehensive overview of RA, including a general introduction to the disease, historical events, epidemiology, risk factors, and pathological process, highlight the primary research progress

SUBMITTER: Ding Q 

PROVIDER: S-EPMC9935929 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature