Screening and identification of hub-gene associated with brain metastasis in breast cancer.

ABSTRACT:

Background

The presence of breast cancer in the brain, also known as brain metastasis (BMS), is the primary reason for a bad prognosis in cases of breast cancer. Breast cancer is the most prevalent malignant tumor seen in women in developing nations. At present, there is no effective method to inhibit brain metastasis of breast cancer. Therefore, it is necessary to conduct a systematic study on BMS of breast cancer, which will not provide ideas and sites for follow-up studies on the treatment and inhibition of BMS.

Methods

In this study, data set GSE43837 was screened from gene expression omnibus database, and then R language tool was used for differential analysis of its expression spectrum, The gene ontology functional enrichment and Kyoto encyclopedia of genes and genomes

SUBMITTER: Li XG 

PROVIDER: S-EPMC9935999 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature