Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.

ABSTRACT: Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal human pancreas tissue resected adjacent to a large tumour. They use TP53 and SMAD4 staining to relate the small focus to the primary tumour. This report describes a represents a probable case of intraparenchymal metastasis of pancreatic cancer, revealing a probable cause of local recurrence.

SUBMITTER: Kiemen AL 

PROVIDER: S-EPMC9936623 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature