Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.
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ABSTRACT:
SUBMITTER: Kiemen AL
PROVIDER: S-EPMC9936623 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.
Kiemen Ashley L AL Choi YoungGeun Y Braxton Alicia M AM Almagro Pérez Cristina C Graham Sarah S Grahn Mia P MP Nanda Neha N Roberts Nicholas N Wood Laura L Wu PeiHsun P Hruban Ralph H RH Wirtz Denis D
Histopathology 20221121 3
Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal human pancreas tissue resected adjacent to a large tumour. They use TP53 and SMAD4 staining to relate the small focus to the primary tumour. This report describes a represents a probable case of intraparenchymal metastasis of pancreatic cancer, revealing a probable cause of local recurrence. ...[more]
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