CytoSaLPs score: a promising new tool for the detection and screening of extrauterine high grade serous carcinoma.

ABSTRACT:

Background

A recent theory supports that high-grade serous epithelial ovarian cancer derives from the fimbrial end of the fallopian tube and during the last decade, a few studies have examined the fallopian tube cytology. Our study aims to determine the cytomorphological characteristics of both benign and non-benign salpingeal samples, in order to establish fallopian cytology as a valuable diagnostic test for women with high risk for development of ovarian/fallopian/peritoneal cancer.

Methods

Our study included patients undergoing salpingoophorectomy or total hysterectomy and salpingoophorectomy for any gynecological pathology. Using a soft brush, fallopian tube smears from the fimbrial end were collected ex vivo. The Cytologists of our Institution described the morphologica

SUBMITTER: Lekka S 

PROVIDER: S-EPMC9936677 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature