Loperamide-induced cardiogenic syncope: a case report of a life-threatening presentation of an over-the-counter drug.

ABSTRACT:

Background

Loperamide at supratherapeutic doses can cause cardiac toxicity, presenting as cardiogenic shock, prolonged QT, malignant arrhythmias, or in severe cases sudden cardiac death. Surreptitious loperamide use is difficult to diagnose. We present an interesting case of loperamide use presenting with polymorphic ventricular tachycardia, cardiogenic shock.

Case summary

A 25-year-old female presented with multiple syncopal episodes for 12 months with an electrocardiogram showing a Brugada-like pattern for which she underwent implantable cardioverter-defibrillator placement. One day following the procedure, she developed cardiogenic shock and was transferred to our tertiary care centre. Extensive workup was unrevealing. She responded well to supportive management, recoveri

SUBMITTER: Hegde V 

PROVIDER: S-EPMC9937037 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature