Atopic dermatitis and risk of gastroesophageal reflux disease: A nationwide population-based study.

ABSTRACT:

Background

As atopic dermatitis (AD) has been found to be related to various comorbidities as well as substantial patient burden, questions of a possible relationship between AD and nonallergic diseases beyond allergic diseases have also been raised.

Objective

The aim of this nationwide matched cohort study was to evaluate whether AD would increase the development of gastroesophageal reflux disease (GERD).

Methods

Patients diagnosed with AD were identified from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) 2.0 database in South Korea from 2002 to 2015. Finally, 9,164 adults with AD (≥20 years old) and age, sex, household income, region of residence, disability, and baseline year-matched 9,164 controls were included in the analysis. Hazard rat

SUBMITTER: Lee SW 

PROVIDER: S-EPMC9937456 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature