A genome-wide association study (GWAS) of the personality constructs in CPAI-2 in Taiwanese Hakka populations.

ABSTRACT: Here in this study we adopted genome-wide association studies (GWAS) to investigate the genetic components of the personality constructs in the Chinese Personality Assessment Inventory 2 (CPAI-2) in Taiwanese Hakka populations, who are likely the descendants of a recent admixture between a group of Chinese immigrants with high emigration intention and a group of the Taiwanese aboriginal population generally without it. A total of 279 qualified participants were examined and genotyped by an Illumina array with 547,644 SNPs to perform the GWAS. Although our sample size is small and that unavoidably limits our statistical power (Type 2 error but not Type 1 error), we still found three genomic regions showing strong association with Enterprise, Diversity, and Logical vs. Affective Orientation,

SUBMITTER: Kao PY 

PROVIDER: S-EPMC9937499 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature