The Effect of Colchicine on Atrial Fibrillation: A Systematic Review and Meta-Analysis.

ABSTRACT: Colchicine is a potent anti-inflammatory agent whose benefits have been explored for various conditions, including atrial fibrillation (AF). In this article, we tried to understand why colchicine might be beneficial in AF and reviewed various studies that looked at the effect of colchicine against AF. We followed the PRISMA algorithm and undertook a literature search to identify studies with control groups that looked at the effect of colchicine against AF and conducted a meta-analysis. We identified six studies on post-cardiac surgical patients, three on post-pulmonary vein isolation (PVI)/ablation patients, and two on coronary artery disease. In patients who underwent cardiac surgery, we found that colchicine is beneficial against postoperative atrial fibrillation (POAF) with a relative

SUBMITTER: Kommu S 

PROVIDER: S-EPMC9937735 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature