Ultrasonic surface acoustic wave-assisted separation of microscale droplets with varying acoustic impedance.

ABSTRACT: In droplet-based microfluidic platforms, precise separation of microscale droplets of different chemical composition is increasingly necessary for high-throughput combinatorial chemistry in drug discovery and screening assays. A variety of droplet sorting methods have been proposed, in which droplets of the same kind are translocated. However, there has been relatively less effort in developing techniques to separate the uniform-sized droplets of different chemical composition. Most of the previous droplet sorting or separation techniques either rely on the droplet size for the separation marker or adopt on-demand application of a force field for the droplet sorting or separation. The existing droplet microfluidic separation techniques based on the in-droplet chemical composition are still

SUBMITTER: Ali M 

PROVIDER: S-EPMC9938309 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature