Lower testosterone levels are associated with higher risk of death in men.

ABSTRACT:

Background and objectives

Testosterone plays an important role in regulating male development, reproduction and health. Declining levels across the lifespan may reflect, or even contribute to, chronic disease and mortality in men.

Methodology

Relationships between testosterone levels and male mortality were analyzed using data from multiple samples of the cross-sectional National Health and Nutrition Examination Survey (n = 10 225). Target outcomes included known deaths from heart disease, malignant neoplasms, chronic lower respiratory diseases, cerebrovascular diseases, Alzheimer's disease, diabetes mellitus, influenza and pneumonia, kidney diseases, and accidents or unintentional injuries.

Results

Results of discrete-time hazard models revealed that lower lev

SUBMITTER: Muehlenbein MP 

PROVIDER: S-EPMC9938530 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature