Analysis of risk characteristics for metachronous metastasis in different period of nasopharyngeal carcinoma.

ABSTRACT:

Objective

To identify the main risk factors for metachronous metastatic nasopharyngeal carcinoma (NPC) in different periods after radiotherapy and estimate the weight of various factors in the early or late metachronous metastasis (EMM/LMM) groups.

Methods

This retrospective registry consists of 4434 patients with newly diagnosed NPC. Cox regression analysis was used to assess the independent significance of various risk factors. The Interactive Risk Attributable Program (IRAP) was used to calculate the attributable risks (ARs) for metastatic patients during different periods.

Results

Among 514 metastatic patients, 346 (67.32%) patients diagnosed with metastasis within 2 years after treatment were classified into the EMM group, while other 168 patients were classified

SUBMITTER: Fei Z 

PROVIDER: S-EPMC9938628 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature