Assisted reproductive technology and association with childhood cancer subtypes.

ABSTRACT:

Objectives

To investigate the association between assisted reproductive technology (ART) use and childhood cancer subtype.

Study design

We deployed a cross-sectional survey of 1701 parents of children with cancer about their ART use, demographics, and gestational and perinatal factors. Multivariable logistic regression modeled the association between ART use, birthweight and multiple gestation status with childhood cancer, by subtype.

Results

ART use was highest among children with osteosarcoma relative to children with other cancer types, and this association was statistically significant in multivariable models (OR = 4.4; 95% CI = 1.7-11.3; p = 0.0020). ART use was also elevated among children with hepatoblastoma, but this relationship appeared to be due to the stro

SUBMITTER: Gulrajani NB 

PROVIDER: S-EPMC9939138 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature