TACE versus TARE for patients with hepatocellular carcinoma: Overall and individual patient level meta analysis.

ABSTRACT:

Background

Transarterial radioembolization (TARE) is increasingly used as an alternative to transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma (HCC). We aimed to perform an overall and individual patient data (IPD) meta-analysis of studies comparing TACE and TARE.

Methods

We performed a systematic literature search using pre-specified keywords with the aid of an informationist for articles from inception to 3/2020. The primary endpoint was overall survival (OS), and the secondary endpoint was time to progression (TTP).

Results

Seventeen studies met inclusion criteria with 2465 unique patients, with one randomized trial, 4 prospective studies and 12 retrospective studies. Barcelona Clinic Liver Cancer (BCLC) stage B (42.8%) was the mos

SUBMITTER: Brown AM 

PROVIDER: S-EPMC9939158 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature