Scope and Consistency of Cancer Outcomes Reported in Randomized Trials in Kidney Transplant Recipients.

ABSTRACT:

Introduction

Cancer is an important outcome in kidney transplantation, but the scope and consistency of how cancer is defined and reported in trials involving kidney transplant recipients has not been evaluated. This study aimed to assess the range and variability of cancer outcomes in trials involving kidney transplant recipients.

Methods

The ClinicalTrials.gov database was searched from February 2000 to July 2021 to identify all randomized controlled trials (RCTs) in adult kidney transplant recipients, and which included cancer as a specified outcome. The definition of cancer, types of cancer (if any), timepoint(s) of measurement and method of aggregation were extracted for each cancer outcome.

Results

Of the 819 trials in kidney transplantation, only 84 (10%) inclu

SUBMITTER: Au EH 

PROVIDER: S-EPMC9939355 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature