Associations of Serum and Dialysate Potassium Concentrations With Incident Atrial Fibrillation in a Cohort Study of Older US Persons Initiating Hemodialysis for Kidney Failure.

ABSTRACT:

Introduction

Atrial fibrillation (AF) disproportionally affects persons on maintenance hemodialysis (HD). Associations of serum and dialysate potassium concentrations [K⁺] with AF incidence are poorly understood.

Methods

We conducted a cohort study using Medicare claims merged with clinical data from a dialysis provider to determine whether serum-[K⁺] and/or dialysate-[K⁺] independently associated with AF incidence. Persons insured by fee-for-service Medicare aged ≥67 years at dialysis initiation and free from diagnosed AF prior to day 120 of dialysis were eligible. Serum-[K⁺] and dialysate-[K⁺] were assessed in 30-day intervals and patients were followed-up with for AF incidence in subsequent 30-day intervals.

Result

SUBMITTER: Hu A 

PROVIDER: S-EPMC9939356 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature