Chronic stress boosts systemic inflammation and compromises antiviral innate immunity in Carassius gibel.

ABSTRACT: It is generally considered that stress causes decreased immune function and render fish vulnerable to infection and diseases. However, the molecular mechanisms between stress responses and susceptibility to infections, especially viral diseases, in fish remain unknown. Understanding and monitoring the biological consequences and mechanisms underlying stress responses in fish may contribute to the improvement of animal welfare and production efficiency. In this study, long-term exposure to a variety of stressors, including chasing, overcrowding, restraint stress, and air exposure mimicking chronic stresses, in aquaculture practices was conducted in Carassius gibel to investigate the consequences of chronic stress on inflammation and antiviral capability. With the continuation of stim

SUBMITTER: Dai C 

PROVIDER: S-EPMC9939519 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature