Effects of kiwi fruit (Actinidia chinensis) polysaccharides on metabolites and gut microbiota of acrylamide-induced mice.

ABSTRACT:

Introduction

Kiwifruit (Actinidia chinensis) has rich nutritious and medicinal properties. It is widely consumed worldwide for the intervention of metabolism disorders, however, the underlying mechanism remains unclear. Acrylamide, a well-known toxic ingredient, mainly forms in high-temperature processed carbohydrate-rich food and causes disorders of gut microbiota and systemic metabolism.

Methods

This study explored the protective effects and underlying mechanisms of kiwifruit polysaccharides against acrylamide-induced disorders of gut microbiota and systemic metabolism by measuring the changes of gut microbiota and serum metabolites in mice.

Results

The results showed that kiwifruit polysaccharides remarkably alleviated acrylamide-induced toxicity in mice by

SUBMITTER: Chen M 

PROVIDER: S-EPMC9939636 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature