Blood transcriptome reveals immune and metabolic-related genes involved in growth of pasteurized colostrum-fed calves.

ABSTRACT: The quality of colostrum is a key factor contributing to healthy calf growth, and pasteurization of colostrum can effectively reduce the counts of pathogenic microorganisms present in the colostrum. Physiological changes in calves fed with pasteurized colostrum have been well characterized, but little is known about the underlying molecular mechanisms. In this study, key genes and functional pathways through which pasteurized colostrum affects calf growth were identified through whole blood RNA sequencing. Our results showed that calves in the pasteurized group (n = 16) had higher body height and daily weight gain than those in the unpasteurized group (n = 16) in all months tested. Importantly, significant differences in body height were observed at 3 and 4 months of age (

SUBMITTER: Li C 

PROVIDER: S-EPMC9939824 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature