Preserved ratio impaired spirometry with or without restrictive spirometric abnormality.

ABSTRACT: Preserved ratio impaired spirometry (PRISm) is defined by reduced FEV₁ with a preserved FEV₁/FVC ratio; some individuals with PRISm can also have restrictive ventilatory abnormality. The aim of this study was to clarify clinical features of restrictive and non-restrictive PRISm. In total, 11,246 participants (mean, 49.1 years; range, 35-65 years) from five healthcare centres were included in this study. We evaluated baseline characteristics of participants with restrictive PRISm (FEV₁/FVC ≥ 0.7, FEV₁ < 80% and FVC < 80%) and non-restrictive PRISm (FEV₁/FVC ≥ 0.7, FEV₁ < 80% and FVC ≥ 80%), and airflow obstruction (FEV₁/FVC < 0.7). We examined the longitudinal risk of developing airflow obstruction by comparing spi

SUBMITTER: Miura S 

PROVIDER: S-EPMC9941093 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature