A tool to enhance antimicrobial stewardship using similarity networks to identify antimicrobial resistance patterns across farms.

ABSTRACT: Antimicrobial resistance (AMR) is one of the major challenges of the century and should be addressed with a One Health approach. This study aimed to develop a tool that can provide a better understanding of AMR patterns and improve management practices in swine production systems to reduce its spread between farms. We generated similarity networks based on the phenotypic AMR pattern for each farm with information on important bacterial pathogens for swine farming based on the Euclidean distance. We included seven pathogens: Actinobacillus suis, Bordetella bronchiseptica, Escherichia coli, Glaesserella parasuis, Pasteurella multocida, Salmonella spp., and Streptococcus suis; and up to seventeen antibiotics from ten classes. A threshold criterion was developed to reduce the density of the ne

SUBMITTER: Aguilar-Vega C 

PROVIDER: S-EPMC9941107 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature