Changing role of the amygdala in affective and cognitive traits between early and late adulthood.

ABSTRACT:

Introduction

Healthy aging is typically associated with cognitive decline and lower negative affect. Previous studies have reported a significant and opposite role of the amygdala in relation to cognitive and affective processing in early adulthood. However, it remains unclear how aging impacts such relationships.

Methods

Seventy-seven healthy participants including 40 young (mean age = 26.1 years) and 37 older (mean age = 61.8 years) adults completed a functional MRI Affective Stroop (AS) paradigm, a cognitive battery, and the state-trait anxiety inventory. The AS fMRI paradigm included "task trials," where participants saw a positively, negatively or neutrally valenced distractor image, followed by a numerical display, followed by another distractor image. We extracted sig

SUBMITTER: Doucet GE 

PROVIDER: S-EPMC9941165 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature