Safety and Effectiveness of Maternal COVID-19 Vaccines Among Pregnant People and Infants.

ABSTRACT: Evidence has consistently demonstrated that COVID-19 messenger RNA (mRNA) vaccines are safe when given during pregnancy. COVID-19 mRNA vaccines protect pregnant people and their infants who are too young to receive COVID-19 vaccines. Although generally protective, monovalent vaccine effectiveness was lower during SARS-CoV-2 Omicron variant predominance, in part due to changes in the Omicron spike protein. Bivalent vaccines, that combine ancestral strain and Omicron variant, may improve protection against Omicron variants. Everyone, including pregnant people, should stay up to date with recommended COVID-19 vaccines and bivalent booster, when eligible.

SUBMITTER: Fleming-Dutra KE 

PROVIDER: S-EPMC9941309 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature