Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit.

ABSTRACT:

Background

Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic drugs, little clinical evidence exists to support this recommendation. This study evaluates the association between prenatal exposure to general anesthesia due to maternal procedures during pregnancy and neuropsychological and behavioral outcome scores at age 10.

Methods

This is an observational cohort study of children born in Perth, Western Australia, with 2 generations of participants contributing data to the Raine Study. In the Raine Study, the first generation (Gen1) are mothers enrolled during pregnancy, and the second generation

SUBMITTER: Ing C 

PROVIDER: S-EPMC9941908 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature