Correlation between osteoprotegerin and coronary artery calcification in diabetic subjects: a systematic review of observational studies.

ABSTRACT: Coronary artery calcification (CAC) is one of the critical cardiovascular complications that lead to elevated morbidity and mortality among patients with type 2 diabetes (T2M). The association between osteoprotegerin (OPG) and CAC could potentially provide a reasonable chance for preventive therapy in type 2 diabetic patients and benefit the rate of mortality. Since measurement of CAC score is relatively expensive and requires radiation exposure, the current systematic review aims to provide clinical evidence for evaluating the prognostic role of OPG in determining CAC risk among subjects with T2M. Web of Science, PubMed, Embase, and Scopus, were investigated until July 2022. We assessed human studies investigating the association of OPG with CAC in type 2 diabetic patients. Quality assess

SUBMITTER: Vazirian F 

PROVIDER: S-EPMC9942374 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature