Diversity and Prevalence of Clostridium innocuum in the Human Gut Microbiota.

ABSTRACT: Clostridia are a polyphyletic group of Gram-positive, spore-forming anaerobes in the Firmicutes phylum that significantly impact metabolism and functioning of the human gastrointestinal tract. Recently, Clostridia were divided into two separate classes, Clostridia and Erysipelotrichia, based on phenotypic and 16S rRNA gene-based differences. While Clostridia include many well-known pathogenic bacteria, Erysipelotrichia remain relatively uncharacterized, particularly regarding their role as a pathogen versus commensal. Despite wide recognition as a commensal, the erysipelotrichial species Clostridium innocuum has recently been associated with various disease states. To further understand the ecological and potential virulent role of C. innocu

SUBMITTER: Bhattacharjee D 

PROVIDER: S-EPMC9942572 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature