Factors related to compliance with adjuvant chemotherapy in patients with gastric cancer: A retrospective single-center study.

ABSTRACT:

Purpose

Adjuvant chemotherapy (AC) improves survival outcomes in patients with advanced gastric cancer (GC) after curative surgery; however, some patients do not receive or complete chemotherapy. This study aimed to identify factors related to patient compliance with chemotherapy after curative surgery for advanced GC.

Methods

The data of patients who underwent curative gastrectomy for pathologic stage II-III GC between 2012 and 2016 were reviewed. Patients were divided into an AC completion group (group C), AC incompletion group (group I), and surgery-only group (group S). The AC regimen was either tegafur/gimeracil/oteracil (S-1) or capecitabine plus oxaliplatin (XELOX).

Results

The study enrolled 417 patients; group C had 222 patients, group I had 110, and group S

SUBMITTER: Jin GY 

PROVIDER: S-EPMC9942746 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature