Effect of a multifaceted antibiotic stewardship intervention to improve antibiotic prescribing for suspected urinary tract infections in frail older adults (ImpresU): pragmatic cluster randomised controlled trial in four European countries.

ABSTRACT:

Objective

To evaluate whether antibiotic prescribing for suspected urinary tract infections in frail older adults can be reduced through a multifaceted antibiotic stewardship intervention.

Design

Pragmatic, parallel, cluster randomised controlled trial, with a five month baseline period and a seven month follow-up period.

Setting

38 clusters consisting of one or more general practices (n=43) and older adult care organisations (n=43) in Poland, the Netherlands, Norway, and Sweden, from September 2019 to June 2021.

Participants

1041 frail older adults aged 70 or older (Poland 325, the Netherlands 233, Norway 276, Sweden 207), contributing 411 person years to the follow-up period.

Intervention

Healthcare professionals received a multifaceted antibiotic stew

SUBMITTER: Hartman EAR 

PROVIDER: S-EPMC9943914 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature