Suppression of top-down influence decreases both behavioral and V1 neuronal response sensitivity to stimulus orientations in cats.

ABSTRACT: How top-down influence affects behavioral detection of visual signals and neuronal response sensitivity in the primary visual cortex (V1) remains poorly understood. This study examined both behavioral performance in stimulus orientation identification and neuronal response sensitivity to stimulus orientations in the V1 of cat before and after top-down influence of area 7 (A7) was modulated by non-invasive transcranial direct current stimulation (tDCS). Our results showed that cathode (c) but not sham (s) tDCS in A7 significantly increased the behavioral threshold in identifying stimulus orientation difference, which effect recovered after the tDCS effect vanished. Consistently, c-tDCS but not s-tDCS in A7 significantly decreased the response selectivity bias of V1 neurons for stimulus orie

SUBMITTER: Ye Z 

PROVIDER: S-EPMC9944033 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature