Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor-Positive Breast Cancer.

ABSTRACT:

Importance

While low income has been associated with a higher incidence of triple-negative breast cancer, its association with 21-gene recurrence score (RS) among patients with estrogen receptor (ER)-positive breast cancer remains unclear.

Objective

To evaluate the association of household income with RS and overall survival (OS) among patients with ER-positive breast cancer.

Design, setting, and participants

This cohort study used data from the National Cancer Database. Eligible participants included women diagnosed between 2010 and 2018 with ER-positive, pT1-3N0-1aM0 breast cancer who received surgery followed by adjuvant endocrine therapy with or without chemotherapy. Data analysis was performed from July 2022 to September 2022.

Exposures

Low vs high neighbo

SUBMITTER: Ma SJ 

PROVIDER: S-EPMC9945075 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature