Overweight and obesity in adult patients with phenylketonuria: a systematic review.

ABSTRACT:

Background

Excess weight is a rising concern in patients with phenylketonuria (PKU). It is commonly observed in children and adolescents with PKU; but data on adults are inconsistent. This review aims to summarize available data on excess weight in adult PKU individuals.

Methods

We conducted a systematic search of literature in English, from inception to October 2021, on PubMed and Embase to identify articles on overweight and obesity in adult PKU patients. Prevalence of overweight and obesity, body mass index (BMI) and gender differences were the outcomes of interest.

Results

Of 260 articles identified, only 8 fulfilled quality criteria for inclusion after screening of titles, abstracts and full texts. The mean BMI of adult PKU patients in these studies ranged from 2

SUBMITTER: Tankeu AT 

PROVIDER: S-EPMC9945382 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature