Cytosolic and mitochondrial ribosomal proteins mediate the locust phase transition via divergence of translational profiles.

ABSTRACT: The phase transition from solitary to gregarious locusts is crucial in outbreaks of locust plague, which threaten agricultural yield and food security. Research on the regulatory mechanisms of phase transition in locusts has focused primarily on the transcriptional or posttranslational level. However, the translational regulation of phase transition is unexplored. Here, we show a phase-dependent pattern at the translation level, which exhibits different polysome profiles between gregarious and solitary locusts. The gregarious locusts exhibit significant increases in 60S and polyribosomes, while solitary locusts possess higher peaks of the monoribosome and a specific "halfmer." The polysome profiles, a molecular phenotype, respond to changes in population density. In gregarious locusts, ten

SUBMITTER: Li J 

PROVIDER: S-EPMC9945961 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature