Acupuncture for autophagy in animal models of middle cerebral artery occlusion: A systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Ischemic stroke has high morbidity, disability and mortality rates. The effective treatments recommended by guideline have considerable limitations due to their strict range of adaptation and narrow time window. Acupuncture is an effective and safe treatment for ischemic stroke, and the mechanism may be related to autophagy. In this systematic review, we aim to summarize and evaluate the evidence of autophagy in acupuncture therapy for animal models of middle cerebral artery occlusion (MCAO).

Methods

Publications will be retrieved from the MEDLINE, Embase, Cochrane Library, Web of Science, CNKI, CBM, CVIP and Wanfang databases. We will include animal experimental studies of acupuncture for MCAO, and the control group will receive placebo/sham acupuncture or no t

SUBMITTER: Yuan J 

PROVIDER: S-EPMC9946199 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature