Peripheral brain-derived neurotrophic factor (BDNF) and salivary cortisol levels in college students with different levels of academic stress. Study protocol.

ABSTRACT:

Introduction

Brain-derived neurotrophic factor (BDNF) is essential for brain physiological processes influencing memory and learning. BDNF levels can be affected by many factors, including stress. Stress increase serum and salivary cortisol levels. Academic stress is of the chronic type. BDNF levels can be measure from serum, plasma or platelets, and there is still no standard methodology, which is relevant to ensure reproducibility and comparability between studies.

Hypothesis

(i) BDNF concentrations in serum show greater variability than in plasma. (ii) In college students with academic stress, peripheral BDNF decreases and salivary cortisol increases.

General objective

To standardize plasma and serum collection for BDNF levels and to determine whether academic stre

SUBMITTER: Castillo-Navarrete JL 

PROVIDER: S-EPMC9946253 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature