Ontology highlight
ABSTRACT:
SUBMITTER: Islam ST
PROVIDER: S-EPMC9946355 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Islam Salim T ST Jolivet Nicolas Y NY Cuzin Clémence C Belgrave Akeisha M AM My Laetitia L Fleuchot Betty B Faure Laura M LM Mahanta Utkarsha U Kezzo Ahmad A AA Saïdi Fares F Sharma Gaurav G Fiche Jean-Bernard JB Bratton Benjamin P BP Herrou Julien J Nollmann Marcelo M Shaevitz Joshua W JW Durand Eric E Mignot Tâm T
Science advances 20230222 8
The predatory deltaproteobacterium Myxococcus xanthus uses a helically-trafficked motor at bacterial focal-adhesion (bFA) sites to power gliding motility. Using total internal reflection fluorescence and force microscopies, we identify the von Willebrand A domain-containing outer-membrane (OM) lipoprotein CglB as an essential substratum-coupling adhesin of the gliding transducer (Glt) machinery at bFAs. Biochemical and genetic analyses reveal that CglB localizes to the cell surface independently ...[more]