Assessing critical temperature dose areas in the kidney by magnetic resonance imaging thermometry in an ex vivo Holmium:YAG laser lithotripsy model.

ABSTRACT:

Purpose

We aimed to assess critical temperature areas in the kidney parenchyma using magnetic resonance thermometry (MRT) in an ex vivo Holmium:YAG laser lithotripsy model.

Methods

Thermal effects of Ho:YAG laser irradiation of 14 W and 30 W were investigated in the calyx and renal pelvis of an ex vivo kidney with different laser application times (t_L) followed by a delay time (t_D) of t_L/t_D = 5/5 s, 5/10 s, 10/5 s, 10/10 s, and 20/0 s, with irrigation rates of 10, 30, 50, 70, and 100 ml/min. Using MRT, the size of the area was determined in which the thermal dose as measured by the Cumulative Equivalent Minutes (CEM₄₃) method exceeded a value of 120 min.

Results

In the calyx, CEM₄₃ never exceeded 120 mi

SUBMITTER: Wriedt R 

PROVIDER: S-EPMC9947089 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature