Simultaneous resection of synchronous colorectal liver metastasis: Feasibility and development of a prediction model.

ABSTRACT:

Backgrounds/aims

Timing of resection for synchronous colorectal liver metastasis (CRLM) has been debated for decades. The aim of the present study was to assess the feasibility of simultaneous resection of CRLM in terms of major complications and develop a prediction model for safe resections.

Methods

A retrospective single-center study of synchronous, resectable CRLM, operated between 2013 and 2021 was conducted. Upper limit of 95% confidence interval (CI) of major complications (≥ grade IIIA) was set at 40% as the safety threshold. Logistic regression was used to determine predictors of morbidity. Prediction model was internally validated by bootstrap estimates, Harrell's C-index, and correlation of predicted and observed estimates.

Results

Ninety-two patients were

SUBMITTER: Kazi M 

PROVIDER: S-EPMC9947373 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature