The role of Gamma Knife radiosurgery in the management of skull base chordoma.

ABSTRACT:

Objective

Chordoma is a slow-growing and locally aggressive cancer, which arises from the remnants of the primitive notochord. The first line treatment for the skull base chordoma is neurosurgery. Gamma Knife radiosurgery (GKS) is often be chosen especially in the setting of residual or recurrent chordomas. The purpose of this study is to evaluate the prognosis of patients with skull base chordoma who underwent GKS.

Methods

The present study was a retrospective analysis of 53 patients with skull base chordomas who underwent GKS. Univariate Cox and Kaplan-Meier survival analysis were performed to analyze the relationship between the tumor control time and the clinical characteristics.

Results

The 1-, 2-, 3-, and 5-year progression free survival (PFS) rates were 87, 71,

SUBMITTER: Wang K 

PROVIDER: S-EPMC9947462 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature