Twenty Years of Quiescence after Nonstop Remicade® (Infliximab) Infusions in a Child with Ocular Behcet Disease Presenting as Hypopyon-Anterior Uveitis Refractory to Immunosuppressants.
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ABSTRACT: I report a case with ocular Behçet disease presenting as hypopyon-anterior uveitis refractory to conventional immunosuppressive drugs who was safely and effectively managed for 20 years by nonstop infusions of a modern anti-TNF agent, infliximab. A 14-year-old girl who had a history of recurrent oro-genital ulcers, arthralgia, and pathergy test positivity presented with the symptoms of bilateral blurred vision, ocular pain, photophobia, and lacrimation. Initial visual acuities were 20/25 bilaterally, and biomicroscopy revealed bilateral iridocyclitis with left shifting cold hypopyon formation in the anterior chamber of the eye. The diagnosis of ocular Behçet disease was made, and topical anti-inflammatory drops were initiated with a cycloplegic agent. In due course, the child complained of
SUBMITTER: Evereklioglu C
PROVIDER: S-EPMC9947665 | biostudies-literature | 2023 Jan-Dec
REPOSITORIES: biostudies-literature
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