In vitro digestion of ESC-resistant Escherichia coli from poultry meat and evaluation of human health risk.

ABSTRACT:

Introduction

The spread of antimicrobial resistance (AMR) has become a threat against human and animal health. Third and fourth generation cephalosporins have been defined as critically important antimicrobials by The World Health Organization. Exposure to Extended spectrum cephalosporin-resistant E. coli may result in consumers becoming carriers if these bacteria colonize the human gut or their resistance genes spread to other bacteria in the gut microbiota. In the case that these resistant bacteria at later occasions cause disease, their resistance characteristics may lead to failure of treatment and increased mortality. We hypothesized that ESC-resistant E. coli from poultry can survive digestion and thereby cause infections and/or spread their respective resistanc

SUBMITTER: Buberg ML 

PROVIDER: S-EPMC9947789 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature