Evaluation of a transbronchial cryoprobe for the ablation of pulmonary nodules: an in vitro pilot study.

ABSTRACT:

Background

Ablation of malignant pulmonary nodules is a novel therapeutic option for patients who cannot undergo surgery. Current transthoracic approaches cause pneumothorax and/or bleeding in a significant number of cases.

Objective

Our purpose with this study was to evaluate cryoablation under in vitro conditions with a commercially available cryosurgery system.

Methods

We used ballistic gelatin to model the thermal conduction of lung tissue. The cryoprobe was inserted in the ballistic gelatin with two thermal sensors, they were placed 0.5 cm and 1.0. cm from the probe, respectively, temperature was measured on both sides. We used single-, double- and triple-freeze protocols to see if we could freeze it to -20 °C.

Results

We achieved - 18.6 ± 3.26 °C on the c

SUBMITTER: Hammer D 

PROVIDER: S-EPMC9948372 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature