Comparative Analysis of Core Microbiome Assignments: Implications for Ecological Synthesis.

ABSTRACT: The concept of a core microbiome has been broadly used to refer to the consistent presence of a set of taxa across multiple samples within a given habitat. The assignment of taxa to core microbiomes can be performed by several methods based on the abundance and occupancy (i.e., detection across samples) of individual taxa. These approaches have led to methodological inconsistencies, with direct implications for ecological interpretation. Here, we reviewed a set of methods most commonly used to infer core microbiomes in divergent systems. We applied these methods using large data sets and analyzed simulations to determine their accuracy in core microbiome assignments. Our results show that core taxa assignments vary significantly across methods and data set types, with occupancy-based metho

SUBMITTER: Custer GF 

PROVIDER: S-EPMC9948721 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature