Volumetric ²³Na Single and Triple-Quantum Imaging at 7T: 3D-CRISTINA.

ABSTRACT:

Purpose

To measure multi-quantum coherence (MQC) ²³Na signals for noninvasive cell physiological information in the whole-brain, the 2D-CRISTINA method was extended to 3D. This experimental study investigated the use and results of a new sequence, 3D-CRISTINA, on a phantom and healthy volunteers.

Methods

The 3D Cartesian single and triple-quantum imaging of ²³Na (3D-CRISTINA) was developed and implemented at 7T, favoring a non-selective volume excitation for increased signal-to-noise ratio (SNR) and lower energy deployment than its 2D counterpart. Two independent phase cycles were used in analogy to the 2D method. A comparison of 6-steps cycles and 12-steps cycles was performed. We used a phantom composed of different sodium and agarose concentrations,

SUBMITTER: Hoesl MAU 

PROVIDER: S-EPMC9948835 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature