Modeling ability to resist alcohol in the human laboratory: A pilot study.

ABSTRACT:

Background

Roughly half of patients with alcohol use disorder prefer non-abstinence based approaches to treatment. However, only individuals who can limit their alcohol use after low-risk consumption are most likely to benefit from these approaches. This pilot study developed a laboratory-based intravenous alcohol self-administration paradigm to determine the characteristics of individuals who could successfully resist consuming alcohol after an initial exposure.

Methods

Seventeen non-treatment seeking heavy drinkers completed two versions of an intravenous alcohol self-administration paradigm designed to assess impaired control over alcohol use. In the paradigm, participants received a priming dose of alcohol and then entered a 120-min resist phase, in which they received m

SUBMITTER: Sloan ME 

PROVIDER: S-EPMC9948911 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature