Integrating Geriatric Assessment Measures into National Cancer Institute Clinical Trials.

ABSTRACT: To improve the care of older adults with cancer, the traditional approach to clinical trial design needs to be reconsidered. Older adults are underrepresented in clinical trials with limited or no information on geriatric-specific factors, such as cognition or comorbidities. To address this knowledge gap and increase relevance of therapeutic clinical trial results to the real-life population, integration of aspects relevant to older adults is needed in oncology clinical trials. Geriatric assessment (GA) is a multidimensional tool comprising validated measures assessing specific health domains that are more frequently affected in older adults, including aspects related to physical function, comorbidity, medication use (polypharmacy), cognitive and psychological status, social support, and n

SUBMITTER: Magnuson A 

PROVIDER: S-EPMC9949568 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature