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An Open Dataset of Annotated Metaphase Cell Images for Chromosome Identification.

ABSTRACT: Chromosomes are a principal target of clinical cytogenetic studies. While chromosomal analysis is an integral part of prenatal care, the conventional manual identification of chromosomes in images is time-consuming and costly. This study developed a chromosome detector that uses deep learning and that achieved an accuracy of 98.88% in chromosomal identification. Specifically, we compiled and made available a large and publicly accessible database containing chromosome images and annotations for training chromosome detectors. The database contains five thousand 24 chromosome class annotations and 2,000 single chromosome annotations. This database also contains examples of chromosome variations. Our database provides a reference for researchers in this field and may help expedite the development of clinical applications.

SUBMITTER: Tseng JJ

PROVIDER: S-EPMC9950090 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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An Open Dataset of Annotated Metaphase Cell Images for Chromosome Identification.

Tseng Jenn-Jhy JJ Lu Chien-Hsing CH Li Jun-Zhou JZ Lai Hui-Yu HY Chen Min-Hu MH Cheng Fu-Yuan FY Kuo Chih-En CE

Scientific data 20230223 1

Chromosomes are a principal target of clinical cytogenetic studies. While chromosomal analysis is an integral part of prenatal care, the conventional manual identification of chromosomes in images is time-consuming and costly. This study developed a chromosome detector that uses deep learning and that achieved an accuracy of 98.88% in chromosomal identification. Specifically, we compiled and made available a large and publicly accessible database containing chromosome images and annotations for ...[more]

PMID: 36823215

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