Genetic diversity of <i>Plasmodium vivax</i> isolates from pregnant women in the Western Brazilian Amazon: a prospective cohort study.

ABSTRACT:

Background

Each year, 92 million pregnant women are at risk of contracting malaria during pregnancy, with the underestimation of the mortality and morbidity burden associated with Plasmodium vivax. During pregnancy, P. vivax infection is associated with low birth weight, maternal anaemia, premature delivery, and stillbirth. In the State of Acre (Brazil), high transmission leaves pregnant women at greater risk of contracting malaria and having a greater number of recurrences. The study of genetic diversity and the association of haplotypes with adverse pregnancy effects is of great importance for the control of the disease. Here we investigate the genetic diversity of P. vivax parasites infecting pregnant women across their pregnancies.

Methods

P. viva

SUBMITTER: Dombrowski JG 

PROVIDER: S-EPMC9950542 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature