Biomarkers of neuroprogression and late staging in bipolar disorder: A systematic review.

ABSTRACT:

Background

Bipolar disorder may undertake a progressive course in a subset of patients, and research efforts have been made to understand the biological basis underlying this process. This systematic review examined the literature available on biological markers associated with illness progression in bipolar disorder.

Methods

Peer-reviewed articles were assessed using Embase, PsycINFO and PubMed, as well as from external sources. After initial screening, a total of 871 citations from databases and other sources were identified. Participants with a diagnosis of bipolar disorder were included in our systematic review; however, studies with participants younger than 15 or older than 65 were excluded. All studies were assessed using the Newcastle-Ottawa Scale assessment tool, an

SUBMITTER: Grewal S 

PROVIDER: S-EPMC9950598 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature