Leveraging intelligent optimization for automated, cardiac-sparing accelerated partial breast treatment planning.

ABSTRACT:

Background

Accelerated partial breast irradiation (APBI) yields similar rates of recurrence and cosmetic outcomes as compared to whole breast radiation therapy (RT) when patients and treatment techniques are appropriately selected. APBI combined with stereotactic body radiation therapy (SBRT) is a promising technique for precisely delivering high levels of radiation while avoiding uninvolved breast tissue. Here we investigate the feasibility of automatically generating high quality APBI plans in the Ethos adaptive workspace with a specific emphasis on sparing the heart.

Methods

Nine patients (10 target volumes) were utilized to iteratively tune an Ethos APBI planning template for automatic plan generation. Twenty patients previously treated on a TrueBeam Edge accelerator wer

SUBMITTER: Pogue JA 

PROVIDER: S-EPMC9950631 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature