Hyperbaric oxygen treatment in the management of necrotising soft-tissue infections: results from a Danish nationwide registry study.

ABSTRACT:

Objectives

Application of hyperbaric oxygen (HBO₂) treatment in the multidisciplinary setting of necrotising soft-tissue infection (NSTI) is debated as a considerable number of studies are of low quality with marked prognostication bias due to inadequately addressing disease severity. The objective of this study was to associate HBO₂ treatment with mortality in patients with NSTI including disease severity as a prognostic variable.

Design

Nationwide population-based register study.

Setting

Denmark.

Participants

Danish residents with NSTI patients between January 2011 and June 2016.

Primary and secondary outcome measures

Thirty-day mortality was compared between patients receiving and patients not receiving HBO₂ treatment

SUBMITTER: Hedetoft M 

PROVIDER: S-EPMC9950903 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature