cis-Selective Hydrogenation of Aryl Germanes: A Direct Approach to Access Saturated Carbo- and Heterocyclic Germanes.

ABSTRACT: A catalytic approach of synthesizing the cis-selective saturated carbo- and heterocyclic germanium compounds (3D framework) is reported via the hydrogenation of readily accessible aromatic germanes (2D framework). Among the numerous catalysts tested, Nishimura's catalyst (Rh₂O₃/PtO₂·H₂O) exhibited the best hydrogenation reactivity with an isolated yield of up to 96%. A broad range of substrates including the synthesis of unprecedented saturated heterocyclic germanes was explored. This selective hydrogenation strategy could tolerate several functional groups such as -CF₃, -OR, -F, -Bpin, and -SiR₃ groups. The synthesized products demonstrated the applications in coupling reactions including the newly developed s

SUBMITTER: Kaithal A 

PROVIDER: S-EPMC9951224 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature